A new study highlights the potential long-term health risks associated with exposure to per- and polyfluoroalkyl substances (PFAS) during pregnancy, suggesting a correlation with increased weight and body fat at age 50. Published on September 5 in The Journal of Clinical Endocrinology & Metabolism, the research underscores the importance of reducing PFAS exposure to mitigate future health risks.
PFAS, often dubbed “forever chemicals,” are persistent in both the environment and human body. They are commonly found in food packaging, cookware, clothing, drinking water, and personal care products. Known for disrupting endocrine functions, these chemicals are linked to a range of health issues, including obesity, infertility, and cancer.
The study, led by Jordan Burdeau, Ph.D., of the Harvard T.H. Chan School of Public Health, analyzed data from 547 pregnant women in their early 30s. It found that those with higher PFAS levels during pregnancy had significantly more body fat and higher weight at age 50 compared to those with lower PFAS exposure. This suggests a potential increased risk of obesity and cardiovascular problems later in life.
“Our findings suggest that pregnancy might be a crucial period for PFAS exposure, influencing long-term weight gain and cardiometabolic health,” Burdeau stated. The study aims to enhance understanding of how PFAS impact health during pregnancy and improve early prevention strategies.
Researchers advise limiting PFAS exposure to potentially reduce the risk of future health issues. The study, funded by the National Institute of Environmental Health Sciences, National Institute of Diabetes and Digestive and Kidney Diseases, and National Institute of Child Health and Human Development, included contributions from experts at Harvard T.H. Chan School of Public Health, Massachusetts General Hospital, Harvard Medical School, and Columbia University Mailman School of Public Health.
